Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610162 | 0.91 | MAPT (0.43) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL6602000 | 0.86 | NOS1 (0.43) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL6598902 | 0.81 | GAA (0.39) | MEN1KMT2AFADS1TRPA1CYP1A2 | |
| SCHEMBL628902 | 0.79 | KDM4E (0.39) | MEN1KMT2AFADS1TRPA1CYP1A2 | |
| SCHEMBL6599982 | 0.76 | TRPA1 (0.44) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL6601877 | 0.74 | MAPT (0.44) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL4322598 | 0.71 | MAPT (0.47) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL4322602 | 0.71 | MAPT (0.47) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL3534329 | 0.71 | MAPT (0.39) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL6597125 | 0.71 | KDM4E (0.45) | HPGDPOLBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432416-A1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Pharmacia Italia S.p.A. (IT) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028720-A1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2003-04-10 | — | — | WO | disclosed |