Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | PFKFB2 | O60825 | 3/20 | 0.32 |
| ▸ | PFKFB1 | P16118 | 3/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599799 | 0.92 | XDH (0.38) | XDH | |
| SCHEMBL14106844 | 0.88 | XDH (0.35) | XDHPFKFB2PFKFB1PFKFB3 | |
| SCHEMBL6598601 | 0.87 | F2RL3 (0.38) | PFKFB2PFKFB1PFKFB3 | |
| SCHEMBL6599695 | 0.87 | PFKFB3 (0.35) | PFKFB2PFKFB1PFKFB3 | |
| SCHEMBL6597700 | 0.87 | MEN1 (0.34) | XDH | |
| SCHEMBL6598454 | 0.87 | XDH (0.33) | XDH | |
| SCHEMBL6601989 | 0.87 | XDH (0.34) | XDH | |
| SCHEMBL6598004 | 0.87 | XDH (0.34) | XDH | |
| SCHEMBL6599016 | 0.86 | XDH (0.38) | XDHPFKFB2PFKFB1PFKFB3 | |
| SCHEMBL6602878 | 0.85 | PLA2G4A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0880519-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027190-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |