Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.62 |
| ▸ | CNR1 | P21554 | 6/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4942386 | 0.93 | F10 (0.70) | F10CNR1NPSR1F2USP2 | |
| Hydrochloric Acid SCHEMBL5735250 | 0.92 | F10 (0.68) | F10CNR1NPSR1F2USP2 | |
| Trifluoroacetic Acid SCHEMBL6199635 | 0.86 | PKM (0.59) | F10F2USP2 | |
| SCHEMBL6177993 | 0.82 | LMNA (0.67) | F10CNR1USP2LMNATSHR | |
| SCHEMBL5735074 | 0.81 | F10 (0.68) | F10CNR1NPSR1USP2LMNA | |
| SCHEMBL5736345 | 0.81 | F10 (0.68) | F10CNR1NPSR1USP2LMNA | |
| Hydrochloric Acid SCHEMBL5733905 | 0.81 | F10 (0.67) | F10CNR1NPSR1USP2LMNA | |
| Hydrochloric Acid SCHEMBL5733907 | 0.81 | F10 (0.67) | F10CNR1NPSR1USP2LMNA | |
| Hydrochloric Acid SCHEMBL5734077 | 0.81 | F10 (0.67) | F10CNR1NPSR1USP2LMNA | |
| Hydrochloric Acid SCHEMBL5735795 | 0.80 | F10 (0.66) | F10CNR1NPSR1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140839-B1 | HETEROCYCLIC AMIDES AS INHIBITORS OF FACTOR XA | LILLY CO ELI (US) | 2004-03-17 | — | — | EP | disclosed |
| US-6660739-B1 | Heterocyclic amides as inhibitors of factor Xa | ELI LILLY AND COMPANY | 2003-12-09 | — | — | US | disclosed |
| EP-1140839-A1 | HETEROCYCLIC AMIDES AS INHIBITORS OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039092-A1 | HETEROCYCLIC AMIDES AS INHIBITORS OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |