Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | P2RY13 | Q9BPV8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MATK | P42679 | 1/20 | 0.33 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599566 | 1.00 | PRKCQ (0.37) | PRKCQMAPTVCAM1POLBSMN1; SMN2 | |
| SCHEMBL5413674 | 0.79 | STK17A (0.45) | PRKCQMAPTSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL3182626 | 0.65 | PRKCQ (0.50) | PRKCQMAPTPOLBSMN1; SMN2PKM | |
| SCHEMBL4867295 | 0.63 | PIN1 (0.61) | POLBSMN1; SMN2PKMGSK3BPIN1 | |
| Hydrochloric Acid SCHEMBL5422026 | 0.63 | STK17A (0.53) | PRKCQMAPTSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL3847319 | 0.62 | PRKCQ (0.60) | PRKCQMAPTPOLBCYP3A4CYP2C9 | |
| SCHEMBL5410032 | 0.62 | GSK3B (0.54) | PRKCQMAPTSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL3172877 | 0.61 | MAPT (0.55) | PRKCQMAPTPOLBSMN1; SMN2PKM | |
| Alcohol SCHEMBL27702458 | 0.61 | PIN1 (0.55) | MAPTPOLBCYP3A4CYP2C9GSK3B | |
| SCHEMBL16011456 | 0.61 | L3MBTL1 (0.62) | MAPTPOLBSMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453516-A2 | NOVEL TRI-SUBSTITUTED PYRIMIDINES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003032994-A2 | NOVEL TRI-SUBSTITUTED PYRIMIDINES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-04-24 | — | — | WO | disclosed |