SCHEMBL6599701

SCHEMBL6599701

CCOC(=O)CCCOc1ccc(CO)c(OC)c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.52
PTPN1 P18031 4/20 0.48
CYP4F2 P78329 2/20 0.48
CYP4A11 Q02928 2/20 0.48
PDK2 Q15119 2/20 0.47
PDE3B Q13370 1/20 0.47
PDE3A Q14432 1/20 0.47
P2RY12 Q9H244 1/20 0.47
TNF P01375 1/20 0.46
PDE4A P27815 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4C Q08493 1/20 0.44
PDE4D Q08499 1/20 0.44
CYSLTR2 Q9NS75 2/20 0.44
CYSLTR1 Q9Y271 2/20 0.44
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120379 0.84 DHFR (0.48) PTPN1
SCHEMBL16301494 0.84 PDE3B (0.43) PDE3BPDE3AP2RY12ALDH1A1
SCHEMBL30215712 0.84 CD274 (0.46) PDK2PDE3BPDE3AP2RY12ALDH1A1
SCHEMBL29402124 0.84 DHFR (0.48) PTPN1
SCHEMBL14309646 0.81 CNR1 (0.54) ALDH1A1
SCHEMBL2654870 0.81 PTPN1 (0.55) BRD4PTPN1PDK2PDE3BPDE3A
SCHEMBL12036216 0.81 CNR1 (0.48) PDK2PDE3BPDE3AP2RY12ALDH1A1
SCHEMBL1229002 0.80 DHFR (0.53) PTPN1
SCHEMBL5842449 0.80 KDM4E (0.55) BRD4PTPN1PDE3BPDE3AP2RY12
SCHEMBL2134115 0.80 PTPN1 (0.53) BRD4PTPN1PDK2PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431135-B Preparation method of 4- (4-hydroxymethyl-3-methoxyphenoxy) butyric acid 安徽昊帆生物有限公司 2025-04-08 CN disclosed
CN-119431135-A Preparation method of 4- (4-hydroxymethyl-3-methoxyphenoxy) butyric acid 安徽昊帆生物有限公司 2025-02-14 CN disclosed
EP-1170009-B1 Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists FUJISAWA PHARMACEUTICAL CO (JP) 2004-04-07 EP disclosed
EP-0880519-B1 THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FUJISAWA PHARMACEUTICAL CO (JP) 2002-04-17 EP disclosed
EP-1170009-A2 Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-09 EP disclosed
US-5994378-A ANTIALLERGENS; ANTIINFLAMMATORY AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-30 US disclosed