Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CCR9 | P51686 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597888 | 0.86 | CCR2 (0.71) | CCR2ABCB11 | |
| SCHEMBL3961949 | 0.83 | CCR2 (1.00) | CCR2CCR9GPR35 | |
| SCHEMBL5378162 | 0.83 | CCR2 (1.00) | CCR2GPR35 | |
| SCHEMBL6300906 | 0.82 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL3969276 | 0.79 | CCR2 (0.82) | CCR2CCR9GPR35 | |
| SCHEMBL6598061 | 0.79 | CCR2 (0.79) | CCR2ABCB11 | |
| SCHEMBL3957310 | 0.77 | CCR2 (1.00) | CCR2CCR9GPR35 | |
| SCHEMBL3966109 | 0.77 | CCR2 (0.78) | CCR2KMT2AGPR35 | |
| SCHEMBL29845455 | 0.77 | CCR2 (0.81) | CCR2CCR9GPR35 | |
| SCHEMBL7008246 | 0.77 | CCR2 (0.81) | CCR2GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150952-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2004-10-27 | — | — | EP | disclosed |