⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14152061 | 0.81 | HTR3A (0.30) | — | |
| SCHEMBL3879558 | 0.73 | — | — | |
| SCHEMBL7563856 | 0.73 | ADRA2A (0.38) | — | |
| SCHEMBL590533 | 0.69 | AKT2 (0.35) | — | |
| SCHEMBL3598196 | 0.68 | ALOX5AP (0.34) | — | |
| SCHEMBL14151705 | 0.68 | CPA1 (0.34) | — | |
| SCHEMBL1181592 | 0.67 | S1PR3 (0.34) | — | |
| SCHEMBL3421366 | 0.67 | CHRM2 (0.35) | — | |
| SCHEMBL3598537 | 0.67 | KDM4E (0.36) | — | |
| SCHEMBL9347230 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120835-B2 | Phosphoric acid ester derivatives | DAIICHI SANKYO COMPANY LIMITED (JP) | 2015-09-01 | — | — | US | disclosed |
| EP-2537831-B1 | IMIDAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-20140135292-A1 | Phosphoric Acid Ester Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-05-15 | — | — | US | disclosed |
| EP-2727926-A1 | PHOSPHORIC ACID ESTER DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8653126-B2 | Imidazole derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-02-18 | — | — | US | disclosed |
| EP-2537831-A1 | IMIDAZOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-20120316170-A1 | Imidazole Derivative | DAIICHI SANKYO COMPANY LIMITED (JP) | 2012-12-13 | — | — | US | disclosed |
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |
| EP-1169320-A4 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2002-10-30 | — | — | EP | disclosed |
| EP-1169320-A1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG Chem Investment, Ltd. (KR) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000064891-A1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2000-11-02 | — | — | WO | disclosed |