Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.63 |
| ▸ | FNTB | P49356 | 7/20 | 0.63 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601972 | 0.91 | FNTA (0.62) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6599882 | 0.89 | FNTA (0.59) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6598192 | 0.89 | FNTA (0.77) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6599904 | 0.84 | FNTA (0.56) | FNTAFNTBPGGT1BCYP3A4LMNA | |
| SCHEMBL6598941 | 0.81 | FNTA (0.73) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6596849 | 0.80 | FNTA (0.71) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL2287583 | 0.78 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6600154 | 0.77 | FNTA (0.66) | FNTAFNTBPGGT1BCYP3A4LMNA | |
| SCHEMBL7087230 | 0.77 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6600381 | 0.74 | FNTA (0.41) | FNTAFNTBPGGT1BCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |