Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6599198 | 0.75 | HTR1A (0.98) | HTR1AALDH1A1KDM4ELMNATSHR | |
| Hydrochloric Acid SCHEMBL6598101 | 0.74 | HTR1A (0.98) | HTR1AALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6599252 | 0.72 | HTR1A (0.98) | HTR1AALDH1A1KDM4ELMNATSHR | |
| Hydrochloric Acid SCHEMBL5358985 | 0.72 | HTR1A (0.55) | HTR1AALDH1A1KDM4ELMNATSHR | |
| SCHEMBL6596142 | 0.72 | HTR1A (1.00) | HTR1AALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6599417 | 0.71 | HTR1A (0.96) | HTR1AALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5364629 | 0.71 | HTR1A (0.67) | HTR1AALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7934844 | 0.70 | ALDH1A1 (0.65) | HTR1AALDH1A1LMNAMPIKMT2A | |
| Hydrochloric Acid SCHEMBL8822122 | 0.69 | HTR1A (0.57) | HTR1AALDH1A1LMNAKMT2A | |
| SCHEMBL17549635 | 0.69 | ALDH1A1 (0.79) | HTR1AALDH1A1KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | disclosed |