Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252175 | 0.61 | INMT (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL14884816 | 0.61 | — | — | |
| SCHEMBL3289230 | 0.48 | — | — | |
| SCHEMBL6965410 | 0.48 | — | — | |
| SCHEMBL100842 | 0.39 | — | — | |
| SCHEMBL1830181 | 0.37 | — | — | |
| SCHEMBL1576988 | 0.37 | — | — | |
| SCHEMBL1381999 | 0.36 | — | — | |
| SCHEMBL106101 | 0.34 | — | — | |
| SCHEMBL9196460 | 0.32 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924210-B1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | WYETH K K (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-0632039-B1 | 2-[1-(1,3-Thiazolin-2-yl)azetidin-3-yl]thio-carbapenem derivatives | WYETH LEDERLE JAPAN LTD (JP) | 2002-01-30 | — | — | EP | disclosed |
| EP-0717042-B1 | Process for preparing 1-(4,5-Dihydro-2-thiazolyle)-3-azetidine thiol derivatives | WYETH LEDERLE JAPAN LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0924210-A1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | LEDERLE (JAPAN), Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5783703-A | CARBAPENEM INTERMEDIATES | LEDERLE (JAPAN), LTD. (JP) | 1998-07-21 | — | — | US | disclosed |
| US-5679790-A | ANTIBIOTICS, BACTERICIDES | LEDERLE (JAPAN), LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| US-5679790-A | ANTIBIOTICS, BACTERICIDES | LEDERLE (JAPAN), LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| US-5659043-A | BACTERICIDES | LEDERLE (JAPAN) LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5534510-A | ORALLY ADMINISTRABLE THIENAMYCIN ANTIBIOTICS; BETA-LACTAMASE INHIBITORS | LEDERLE (JAPAN), LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| US-5534510-A | ORALLY ADMINISTRABLE THIENAMYCIN ANTIBIOTICS; BETA-LACTAMASE INHIBITORS | LEDERLE (JAPAN), LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0717042-A1 | 1-(4,5-Dihydro-2-thiazolyle)-3-azetidine thiol derivatives | LEDERLE (JAPAN), Ltd. (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0632039-A1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | LEDERLE (JAPAN), Ltd. (JP) | 1995-01-04 | — | — | EP | disclosed |
| EP-0632039-A1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | LEDERLE (JAPAN), Ltd. (JP) | 1995-01-04 | — | — | EP | disclosed |