SCHEMBL252175

SCHEMBL252175

C1CN=C2SCCCN2C1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
INMT O95050 4/20 0.39
USP2 O75604 1/20 0.39
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
ALDH1A1 P00352 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14884816 0.91
SCHEMBL247326 0.91
SCHEMBL970235 0.84
SCHEMBL18132867 0.82 USP2 (0.39) INMTUSP2NOS3NOS1NOS2
Oxalic Acid SCHEMBL18118015 0.72 HPGD (0.43) INMTALDH1A1
SCHEMBL9847245 0.67 ALDH1A1 (0.31) ALDH1A1HIF1A
SCHEMBL21124042 0.66 NOS3 (0.30) NOS3NOS1NOS2
SCHEMBL11755346 0.64 INMT (0.39) INMTALDH1A1HIF1A
SCHEMBL22060208 0.63 LMNA (0.34)
SCHEMBL6600764 0.61 NOS3 (0.33) NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2665788-A1 CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY 3M Innovative Properties Company (US) 2013-11-27 EP claimed
US-20130102728-A1 CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-25 US claimed
WO-2012003160-A1 CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-05 WO claimed
US-8841399-B2 Curable composition comprising dual reactive silane functionality 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-23 US disclosed
US-8841399-B2 Curable composition comprising dual reactive silane functionality 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-23 US disclosed
US-8841399-B2 Curable composition comprising dual reactive silane functionality 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-23 US disclosed
EP-2665788-A1 CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY 3M Innovative Properties Company (US) 2013-11-27 EP disclosed
US-20130102728-A1 CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-25 US disclosed
US-20130102728-A1 CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-25 US disclosed
US-20130102728-A1 CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-25 US disclosed
WO-2012003160-A1 CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-05 WO disclosed
WO-2012003160-A1 CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-05 WO disclosed