Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 19/20 | 0.77 |
| ▸ | NPY5R | Q15761 | 12/20 | 0.77 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608083 | 0.90 | ADRA2A (0.78) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3937577 | 0.87 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3943763 | 0.87 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3937579 | 0.87 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6601170 | 0.85 | MCHR1 (0.88) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3940717 | 0.85 | MCHR1 (0.81) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL3940720 | 0.85 | MCHR1 (0.81) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13792936 | 0.84 | MCHR1 (0.82) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| Hydrochloric Acid SCHEMBL6612076 | 0.82 | ADRA2A (0.79) | MCHR1ADRA2ANPY5R | |
| SCHEMBL13793721 | 0.81 | MCHR1 (0.73) | MCHR1ADRA2ANPY5RHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432693-A2 | MCH RECEPTOR ANTAGONISTS | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028641-A2 | MCH RECEPTOR ANTAGONISTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2003-04-10 | — | — | WO | disclosed |