Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 19/20 | 0.78 |
| ▸ | MCHR1 | Q99705 | 19/20 | 0.78 |
| ▸ | NPY5R | Q15761 | 15/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6612076 | 0.92 | ADRA2A (0.79) | ADRA2AMCHR1NPY5R | |
| SCHEMBL6601174 | 0.90 | MCHR1 (0.77) | ADRA2AMCHR1NPY5R | |
| SCHEMBL3937588 | 0.88 | MCHR1 (1.00) | ADRA2AMCHR1NPY5R | |
| SCHEMBL3937587 | 0.88 | MCHR1 (1.00) | ADRA2AMCHR1NPY5R | |
| SCHEMBL3938807 | 0.88 | MCHR1 (1.00) | ADRA2AMCHR1NPY5R | |
| SCHEMBL6608079 | 0.86 | MCHR1 (0.89) | ADRA2AMCHR1NPY5R | |
| SCHEMBL13793618 | 0.86 | ADRA2A (0.83) | ADRA2AMCHR1NPY5R | |
| Hydrochloric Acid SCHEMBL3941816 | 0.85 | ADRA2A (0.81) | ADRA2AMCHR1NPY5R | |
| Hydrochloric Acid SCHEMBL6604773 | 0.85 | ADRA2A (0.81) | ADRA2AMCHR1NPY5R | |
| Hydrochloric Acid SCHEMBL6604770 | 0.85 | ADRA2A (0.81) | ADRA2AMCHR1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432693-A2 | MCH RECEPTOR ANTAGONISTS | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028641-A2 | MCH RECEPTOR ANTAGONISTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2003-04-10 | — | — | WO | disclosed |