Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 7/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397133 | 0.91 | POLM (0.50) | PARP14ERAP1KDM4EMEN1KMT2A | |
| SCHEMBL27864646 | 0.91 | POLM (0.50) | PARP14ERAP1KDM4EMEN1KMT2A | |
| SCHEMBL9398516 | 0.91 | POLM (0.50) | PARP14ERAP1KDM4EMEN1KMT2A | |
| SCHEMBL3924071 | 0.90 | PARP14 (0.50) | PARP14ERAP1KIF11KDM4EMEN1 | |
| SCHEMBL29001995 | 0.85 | KIF11 (0.44) | PARP14ERAP1KIF11GABRPGABRD | |
| SCHEMBL31031443 | 0.85 | POLM (0.55) | PARP14KDM4EMEN1KMT2ARECQL | |
| SCHEMBL11584101 | 0.84 | EGFR (0.46) | PARP14ERAP1KIF11KDM4EGABRP | |
| SCHEMBL27747315 | 0.83 | ERAP1 (0.46) | PARP14ERAP1KIF11KDM4EMEN1 | |
| SCHEMBL2429422 | 0.82 | PARP14 (0.51) | PARP14KIF11KDM4EMAPTJAK2 | |
| SCHEMBL4786156 | 0.82 | SLC22A6 (0.55) | PARP14KIF11KDM4EMAPTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110035749-A | FABP4 as a therapeutic target in skin disorders | 蒂库尔有限公司 | 2019-07-19 | — | — | CN | claimed |
| CN-106659765-A | Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer | 德玛医药 | 2017-05-10 | — | — | CN | claimed |
| CN-118103357-A | FABP4/5 inhibitors, methods of use and methods of preparation | 塞洛拉姆股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115998871-A | FABP4 as therapeutic target in dermatological diseases | 蒂库尔有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-106659765-B | Use of dianhydrogalactitol and analogs or derivatives thereof for treating non-small cell lung cancer and ovarian cancer | 德玛医药 | 2021-08-13 | — | — | CN | disclosed |
| CN-110035749-A | FABP4 as a therapeutic target in skin disorders | 蒂库尔有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-106659765-A | Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer | 德玛医药 | 2017-05-10 | — | — | CN | disclosed |
| EP-0923569-B1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6020366-A | Butyric acid matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0923569-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006711-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |