Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 6/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500727 | 0.91 | PARP14 (0.49) | PARP14FTOHSD17B10KIF11TP53 | |
| SCHEMBL11584101 | 0.87 | EGFR (0.46) | PARP14FTOKDM4EHPGDHSD17B10 | |
| SCHEMBL4786156 | 0.84 | SLC22A6 (0.55) | PARP14FTOKDM4EHPGDHSD17B10 | |
| SCHEMBL9676604 | 0.84 | ALDH1A1 (0.59) | PARP14FTOKDM4EHPGDHSD17B10 | |
| SCHEMBL3924071 | 0.84 | PARP14 (0.50) | PARP14FTOKDM4EKIF11TP53 | |
| SCHEMBL15560416 | 0.83 | KIF11 (0.47) | PARP14FTOKDM4EHPGDHSD17B10 | |
| SCHEMBL11537835 | 0.82 | KIF11 (0.45) | PARP14FTOKDM4EHPGDHSD17B10 | |
| SCHEMBL6601301 | 0.82 | PARP14 (0.51) | PARP14FTOKDM4EKIF11TP53 | |
| SCHEMBL29001995 | 0.82 | KIF11 (0.44) | PARP14KIF11TP53MAPTJAK2 | |
| SCHEMBL2935664 | 0.81 | KIF11 (0.44) | PARP14FTOKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011116865-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |