Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601383 | 0.91 | GRM2 (0.48) | GRM2 | |
| SCHEMBL7637118 | 0.89 | ITGB3 (0.48) | GRM2 | |
| SCHEMBL6601789 | 0.89 | GRM2 (0.45) | GRM2 | |
| SCHEMBL6600722 | 0.89 | GRM2 (0.45) | GRM2 | |
| SCHEMBL6600718 | 0.89 | GRM2 (0.45) | GRM2 | |
| SCHEMBL6601596 | 0.89 | GRM2 (0.42) | GRM2 | |
| SCHEMBL6601603 | 0.89 | GRM2 (0.42) | GRM2 | |
| SCHEMBL6605350 | 0.88 | GRM2 (0.44) | GRM2 | |
| SCHEMBL7639664 | 0.87 | ITGB3 (0.44) | GRM2 | |
| SCHEMBL7639772 | 0.87 | ITGB3 (0.55) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |