Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3890994 | 0.93 | ALDH1A1 (0.59) | TPMTALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL2823144 | 0.82 | DHODH (0.51) | ALDH1A1HTTL3MBTL1RXRARXRB | |
| SCHEMBL6918093 | 0.79 | TPMT (0.94) | TPMTALDH1A1HCAR1HPGDRXRA | |
| SCHEMBL221684 | 0.77 | TPMT (1.00) | TPMTALDH1A1HCAR1HPGDRXRA | |
| SCHEMBL3898423 | 0.76 | HTT (0.76) | HTTL3MBTL1HPGDLMNANPC1 | |
| SCHEMBL27894302 | 0.76 | L3MBTL1 (0.55) | ALDH1A1HTTL3MBTL1HPGDGAA | |
| SCHEMBL6918090 | 0.74 | TPMT (0.94) | TPMTALDH1A1HCAR1HPGDRXRA | |
| SCHEMBL6914123 | 0.74 | TPMT (0.94) | TPMTALDH1A1HCAR1HPGDRXRA | |
| SCHEMBL6916035 | 0.74 | TPMT (0.94) | TPMTALDH1A1HCAR1HPGDRXRA | |
| SCHEMBL6918621 | 0.74 | TPMT (0.94) | TPMTALDH1A1HCAR1HPGDRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402900-A1 | MEDICINAL COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| EP-1354603-A1 | CONCOMITANT DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-22 | — | — | EP | disclosed |