Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5417761 | 0.99 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL28694741 | 0.82 | MEN1 (0.73) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9260456 | 0.80 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL29764514 | 0.80 | MEN1 (0.86) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL6061686 | 0.80 | MEN1 (0.86) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9260459 | 0.80 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL12027654 | 0.77 | POLB (0.55) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL12027660 | 0.77 | POLB (0.55) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL16675681 | 0.77 | POLB (0.55) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL16689926 | 0.77 | MC4R (0.56) | TRPM8MC4RMC5RMC3RAGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403255-A1 | Rho KINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-31 | — | — | EP | disclosed |