Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260456 | 1.00 | MEN1 (0.69) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL6061686 | 0.89 | MEN1 (0.86) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL29764514 | 0.89 | MEN1 (0.86) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL25309231 | 0.84 | MEN1 (0.63) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL28694741 | 0.84 | MEN1 (0.73) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL6061687 | 0.84 | MEN1 (0.78) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL5889435 | 0.81 | MEN1 (0.69) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL6601504 | 0.80 | MEN1 (0.57) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL29918604 | 0.79 | MEN1 (0.60) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL6178481 | 0.79 | MEN1 (0.65) | MEN1KMT2ALMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021815-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND SQUALENE SYNTHASE | ABBOTT LABORATORIES (US) | 1995-08-17 | — | — | WO | disclosed |