Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605397 | 0.93 | ITGB3 (0.54) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6601149 | 0.93 | ITGB3 (0.53) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6604810 | 0.91 | ITGB3 (0.52) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL7308588 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6606675 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6601240 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BSIGMAR1TMEM97SLC6A2 | |
| SCHEMBL6601284 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BSIGMAR1TMEM97SLC6A2 | |
| SCHEMBL6606261 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6600714 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6605994 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1TMEM97SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |