Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 7/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604965 | 0.97 | NCF1 (0.64) | NCF1ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL3949621 | 0.87 | NCF1 (0.68) | NCF1ADRB2ADRB1KMT2ANQO2 | |
| SCHEMBL5025365 | 0.85 | NCF1 (0.64) | NCF1ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL6204107 | 0.79 | MCHR1 (0.48) | NCF1KMT2AALDH1A1MEN1GAA | |
| SCHEMBL5420561 | 0.79 | NCF1 (0.64) | NCF1ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL5065450 | 0.78 | NCF1 (0.88) | NCF1ADRB2ADRB1KMT2AMEN1 | |
| SCHEMBL7474699 | 0.78 | NCF1 (0.52) | NCF1KMT2AALDH1A1MEN1 | |
| SCHEMBL3648942 | 0.77 | NCF1 (0.45) | NCF1ADRB2ADRB1KMT2ACHRM4 | |
| SCHEMBL3642882 | 0.77 | NCF1 (0.45) | NCF1ADRB2ADRB1KMT2ACHRM4 | |
| SCHEMBL3643040 | 0.77 | NCF1 (0.45) | NCF1ADRB2ADRB1KMT2ACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |