Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.63 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601833 | 0.92 | ESR1 (0.63) | ESR1ESR2 | |
| SCHEMBL6604899 | 0.88 | ESR1 (0.67) | ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL6601884 | 0.84 | ESR1 (0.61) | ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL6959934 | 0.83 | ESR1 (0.86) | ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL7665997 | 0.83 | ESR1 (0.86) | ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL7663013 | 0.83 | ESR1 (0.86) | ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL7664893 | 0.83 | ESR1 (0.86) | ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL6601387 | 0.83 | ESR1 (0.64) | ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL8492628 | 0.83 | CHRNB2 (0.55) | ESR1ESR2 | |
| SCHEMBL7671368 | 0.82 | ESR1 (0.88) | ESR1ESR2ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905132-B1 | Benzothiophenes | LILLY CO ELI (US) | 2004-08-04 | — | — | EP | disclosed |
| US-6060488-A | ANTICARCINOGENIC AGENTS; POSTMENOPAUSAL CANCER OF BREASTS, UTERUS, CERVIX | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0905132-A1 | Benzothiophenes | ELI LILLY AND COMPANY (US) | 1999-03-31 | — | — | EP | disclosed |