Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 19/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796618 | 0.91 | FKBP1A (0.96) | FKBP1A | |
| SCHEMBL7253232 | 0.84 | FKBP1A (0.88) | FKBP1A | |
| SCHEMBL8099641 | 0.83 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL5966142 | 0.82 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL4677091 | 0.79 | FKBP1A (0.82) | FKBP1A | |
| SCHEMBL7424656 | 0.78 | FKBP1A (0.80) | FKBP1A | |
| SCHEMBL7605473 | 0.78 | FKBP1A (0.55) | FKBP1A | |
| SCHEMBL17921877 | 0.76 | FKBP1A (0.77) | FKBP1A | |
| SCHEMBL17921909 | 0.76 | FKBP1A (0.77) | FKBP1A | |
| SCHEMBL5966132 | 0.75 | FKBP1A (1.00) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992492-B1 | Small molecule inhibitors of rotamase enzyme activity | GUILFORD PHARM INC (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-1996040633-A1 | SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY | GUILFORD PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |