SCHEMBL7424656

SCHEMBL7424656

CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OCCC(CCc1ccccc1)c1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8796618 0.87 FKBP1A (0.96) FKBP1A
SCHEMBL5965946 0.86 FKBP1A (1.00) FKBP1A
SCHEMBL10111024 0.86 FKBP1A (1.00) FKBP1A
SCHEMBL5966094 0.86 FKBP1A (1.00) FKBP1A
SCHEMBL7396367 0.86 FKBP1A (1.00) FKBP1A
SCHEMBL5834555 0.86 FKBP1A (1.00) FKBP1A
SCHEMBL5966032 0.85 FKBP1A (1.00) FKBP1A
SCHEMBL14252542 0.85 FKBP1A (1.00) FKBP1A
SCHEMBL13550161 0.84 FKBP1A (1.00) FKBP1A
SCHEMBL15070993 0.84 FKBP1A (1.00) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002522485-A 2002-07-23 JP claimed
EP-1109554-A2 PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS GPI NIL Holdings, Inc. (US) 2001-06-27 EP claimed
WO-2000009109-A2 PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS GPI NIL HOLDINGS, INC. (US) 2000-02-24 WO claimed
EP-1127049-A1 BRIDGED HETEROCYCLIC DERIVATIVES GPI NIL Holdings, Inc. (US) 2001-08-29 EP disclosed
EP-1109554-A2 PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS GPI NIL Holdings, Inc. (US) 2001-06-27 EP disclosed
WO-2000016603-A2 BRIDGED HETEROCYCLIC DERIVATIVES GPI NIL HOLDINGS, INC. (US) 2000-03-30 WO disclosed
WO-2000009109-A2 PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS GPI NIL HOLDINGS, INC. (US) 2000-02-24 WO disclosed