Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600829 | 0.93 | ITGB3 (0.45) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6601403 | 0.92 | ITGB3 (0.62) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6601660 | 0.92 | ITGB3 (0.59) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6600475 | 0.91 | ITGB3 (0.52) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6603247 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6601152 | 0.90 | ITGB3 (0.52) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6600926 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6602801 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6601254 | 0.88 | ITGB3 (0.50) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6601206 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BSIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451180-A1 | QUINAZOLINE COMPOUNDS WITH THERAPEUTIC USE | Astrazeneca AB (SE) | 2004-09-01 | — | — | EP | claimed |
| WO-2003045943-A1 | QUINAZOLINE COMPOUNDS WITH THERAPEUTIC USE | ASTRAZENECA AB (SE) | 2003-06-05 | — | — | WO | claimed |
| WO-2004087120-A2 | USE OF QUINAZOLINE DERIVATIVES WITH SRC KINASE INHIBITORY ACTIVITY FOR THE TREATMENT OF HYPERTENSION | ASTRAZENECA AB (SE) | 2004-10-14 | — | — | WO | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |