Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097283 | 0.81 | NAAA (0.43) | PYCR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16724088 | 0.81 | PYCR1 (0.40) | ALDH1A1MAPK1TDP1PYCR1SRC | |
| SCHEMBL18348140 | 0.81 | PYCR1 (0.40) | MAPK1PYCR1SRCTSHRSMN1; SMN2 | |
| SCHEMBL12133277 | 0.78 | FFAR4 (0.45) | ALDH1A1TDP1L3MBTL1PYCR1SRC | |
| SCHEMBL15835002 | 0.77 | PTGDR2 (0.37) | ALDH1A1MAPK1TDP1L3MBTL1SRC | |
| SCHEMBL28924 | 0.76 | IDO1 (0.55) | ALDH1A1TSHRSMN1; SMN2MAPTHTT | |
| SCHEMBL12766079 | 0.75 | KDM4E (0.49) | ALDH1A1MAPK1TDP1L3MBTL1ALOX15 | |
| SCHEMBL28523896 | 0.74 | NCEH1 (0.35) | ALDH1A1MAOAMAOBSRCSMN1; SMN2 | |
| SCHEMBL5738944 | 0.74 | HSP90AA1 (0.41) | ALDH1A1MAPK1HSP90AA1TLR9TDP1 | |
| SCHEMBL4799391 | 0.74 | PYCR1 (0.43) | ALDH1A1MAPK1HSP90AA1TLR9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923569-B1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6020366-A | Butyric acid matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | disclosed |