Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602517 | 0.94 | ITGB3 (0.51) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL6607037 | 0.93 | SIGMAR1 (0.44) | SIGMAR1ITGB3ITGA2BGRM2HTR1A | |
| SCHEMBL7306117 | 0.93 | ITGB3 (0.53) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL6603873 | 0.91 | SIGMAR1 (0.44) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL6601642 | 0.90 | SIGMAR1 (0.41) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL6600250 | 0.89 | ITGB3 (0.48) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL6599465 | 0.88 | ITGB3 (0.51) | SIGMAR1ITGB3ITGA2BGRM2PRSS1 | |
| SCHEMBL6602276 | 0.87 | ITGB3 (0.60) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL6601092 | 0.87 | ITGB3 (0.46) | SIGMAR1ITGB3ITGA2BGRM2F10 | |
| SCHEMBL6601631 | 0.87 | ITGB3 (0.48) | SIGMAR1ITGB3ITGA2BGRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388540-A1 | ACRYLIC ESTERS AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2004-02-11 | — | — | EP | disclosed |