Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.64 |
| ▸ | LIPC | P11150 | 1/20 | 0.64 |
| ▸ | LIPE | Q05469 | 1/20 | 0.64 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.43 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.43 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604889 | 0.84 | LPL (0.72) | LPLLIPCLIPEABHD16AORAI1 | |
| SCHEMBL6600553 | 0.84 | LPL (0.62) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL6602937 | 0.79 | ABHD16A (0.60) | LPLLIPCLIPEABHD16ANR3C1 | |
| SCHEMBL7047919 | 0.79 | LPL (1.00) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL7042468 | 0.78 | LPL (0.60) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL6604642 | 0.77 | LPL (0.62) | LPLLIPCLIPEABHD16APTGDR2 | |
| SCHEMBL6603513 | 0.74 | LPL (0.64) | LPLLIPCLIPEABHD16APTGDR2 | |
| SCHEMBL6601943 | 0.74 | LPL (0.72) | LPLLIPCLIPEABHD16AORAI1 | |
| SCHEMBL15917677 | 0.73 | NPC1 (0.58) | PTGDR2GPR27TRPV4TRPV1 | |
| SCHEMBL7044266 | 0.73 | LPL (0.70) | LPLLIPCLIPEABHD16APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |