Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633208 | 0.93 | ITGB3 (0.45) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6606831 | 0.92 | ITGB3 (0.44) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6602652 | 0.92 | ITGB3 (0.55) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6602415 | 0.91 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1F10SMN1; SMN2 | |
| SCHEMBL6600840 | 0.91 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1F10SMN1; SMN2 | |
| SCHEMBL6601254 | 0.91 | ITGB3 (0.50) | ITGB3ITGA2BSIGMAR1SMN1; SMN2CYP1A2 | |
| SCHEMBL6605957 | 0.91 | ITGB3 (0.56) | ITGB3ITGA2BSIGMAR1SMN1; SMN2GRM2 | |
| SCHEMBL6600759 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6600694 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6601822 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |