Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602820 | 0.93 | ITGB3 (0.59) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL7633507 | 0.92 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1SMN1; SMN2GRM2 | |
| SCHEMBL6601254 | 0.92 | ITGB3 (0.50) | ITGB3ITGA2BSIGMAR1SMN1; SMN2GRM2 | |
| SCHEMBL6602058 | 0.91 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6602430 | 0.91 | ITGB3 (0.51) | ITGB3ITGA2BSIGMAR1SMN1; SMN2GRM2 | |
| SCHEMBL6600683 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6604051 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6604052 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL6601226 | 0.90 | ITGB3 (0.50) | ITGB3ITGA2BSIGMAR1SMN1; SMN2GRM2 | |
| Gantofiban SCHEMBL6600995 | 0.89 | ITGB3 (0.70) | ITGB3ITGA2BSIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |