SCHEMBL660283

SCHEMBL660283

CCC1(CC)c2ccccc2-c2ccc(I)cc21

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 13/20 0.36
PGR P06401 2/20 0.36
APEX1 P27695 1/20 0.36
KCNQ2 O43526 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921820 0.91 TDP2 (0.35)
SCHEMBL9781139 0.86 APEX1 (0.41) PDK2PGRAPEX1KCNQ2
SCHEMBL664630 0.83 APEX1 (0.39) PDK2PGRAPEX1CYP2C19
SCHEMBL1271141 0.83 APEX1 (0.41) PDK2PGRAPEX1KCNQ2CYP1A2
SCHEMBL1394829 0.82 APEX1 (0.47) PDK2PGRAPEX1KCNQ2CYP1A2
SCHEMBL29484836 0.82 APEX1 (0.47) PDK2PGRAPEX1KCNQ2CYP1A2
SCHEMBL4632268 0.82 PDK2 (0.39) PDK2PGRAPEX1CYP2C19KMT2A
SCHEMBL2129264 0.81 PDK2 (0.44) PDK2
SCHEMBL1923373 0.81 PDK2 (0.40) PDK2APEX1CYP2C19KMT2A
SCHEMBL1921668 0.81 PDK2 (0.40) PDK2APEX1CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105037167-B A kind of synthetic method of N, N diaryl 2 bromine 6 naphthylamines and its application 华南理工大学 2017-03-01 CN claimed
CN-105037167-A Synthetic method of N, N-diaryl-2-bromine-6-naphthylamine and application thereof UNIV SOUTH CHINA TECH 2015-11-11 CN claimed
CN-105037167-B A kind of synthetic method of N, N diaryl 2 bromine 6 naphthylamines and its application 华南理工大学 2017-03-01 CN disclosed
CN-105037167-A Synthetic method of N, N-diaryl-2-bromine-6-naphthylamine and application thereof UNIV SOUTH CHINA TECH 2015-11-11 CN disclosed
EP-2327739-B1 Novel triarylamine polymer, process for its production and its use TOSOH CORP (JP) 2014-05-07 EP disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
CN-101410356-B Novel compound and organic light emitting device using the same CANON KK 2013-08-07 CN disclosed
US-8384286-B2 Compound and organic light emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2013-02-26 US disclosed
CN-102629663-A Novel compound and organic light emitting device using the compound CANON KK 2012-08-08 CN disclosed
US-20120043535-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2012-02-23 US disclosed
US-8072136-B2 Compound and organic light emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2011-12-06 US disclosed
CN-101410356-A Novel compound and organic light emitting device using the same CANON KK (JP) 2009-04-15 CN disclosed
EP-2004580-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND Canon Kabushiki Kaisha (JP) 2008-12-24 EP disclosed
US-20080297034-A1 BIPHENYL DERIVATIVE AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME CANON KABUSHIKI KAISHA (JP) 2008-12-04 US disclosed
US-20080297034-A1 BIPHENYL DERIVATIVE AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME CANON KABUSHIKI KAISHA (JP) 2008-12-04 US disclosed
WO-2007114038-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2007-10-11 WO disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297034-A1 BIPHENYL DERIVATIVE AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME LEF1, CYP1B1, ESR1 PDK2 1367/4885PGR 1018/4885APEX1 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.