Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601697 | 0.85 | ALDH1A1 (0.70) | CYSLTR2CYSLTR1ALDH1A1SMN1; SMN2KDM4E | |
| Benzene SCHEMBL6364361 | 0.82 | MEN1 (0.66) | CYSLTR2CYSLTR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1495919 | 0.82 | MEN1 (0.66) | CYSLTR2CYSLTR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8355619 | 0.81 | LTB4R (0.56) | CYSLTR2CYSLTR1MAPTMEN1KMT2A | |
| SCHEMBL6608386 | 0.81 | KDM4E (0.52) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL6604313 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL29222762 | 0.78 | KDM4E (0.45) | CYSLTR2CYSLTR1ALDH1A1SMN1; SMN2KDM4E | |
| Acetone SCHEMBL27714910 | 0.78 | KMT2A (0.49) | CYSLTR2CYSLTR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6605120 | 0.77 | ALDH1A1 (0.53) | CYSLTR2CYSLTR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16449538 | 0.77 | KMT2A (0.48) | CYSLTR2CYSLTR1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | claimed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | claimed |
| US-5488027-A | Herbicide-safener combinations containing sulfonylurea or imidazolinone herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-30 | — | — | US | disclosed |