Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657829 | 0.84 | MAPK14 (0.57) | MCL1MAPK14NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11816232 | 0.81 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL6189876 | 0.81 | MAPK14 (0.48) | MAPK14NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL19484711 | 0.79 | CSNK2A1 (0.43) | NPC1RAB9AHPGDALDH1A1GAA | |
| SCHEMBL27537578 | 0.78 | MCL1 (0.73) | MCL1ALDH1A1HSD17B10FTOMYC | |
| SCHEMBL7832639 | 0.77 | RARB (0.56) | MAPK14NPC1RAB9AALDH1A1MAPK11 | |
| SCHEMBL11607903 | 0.77 | RAB9A (0.70) | MCL1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL4943334 | 0.77 | MCL1 (0.71) | MCL1HPGDALDH1A1FTOMYC | |
| SCHEMBL13427116 | 0.77 | RAB9A (0.64) | MAPK14NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL4861805 | 0.77 | MAPK14 (0.57) | MAPK14HPGDALDH1A1MAPK11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436269-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033482-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-04-24 | — | — | WO | disclosed |