Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608789 | 0.85 | LCK (0.66) | LCKCISD2 | |
| SCHEMBL1541226 | 0.82 | LCK (0.71) | LCKCISD2 | |
| SCHEMBL27562367 | 0.81 | LCK (0.50) | LCKCISD2 | |
| SCHEMBL773032 | 0.79 | LCK (0.61) | LCK | |
| SCHEMBL27562374 | 0.79 | LCK (0.50) | LCK | |
| SCHEMBL14568867 | 0.74 | LCK (0.76) | LCK | |
| SCHEMBL7622222 | 0.74 | LCK (0.60) | LCK | |
| SCHEMBL7629232 | 0.73 | LCK (0.45) | LCKCISD2 | |
| SCHEMBL6603764 | 0.73 | LCK (0.56) | LCK | |
| SCHEMBL7631673 | 0.73 | LCK (0.46) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169038-A4 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2004-10-13 | — | — | EP | claimed |
| EP-1169038-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-01-09 | — | — | EP | claimed |
| WO-2000062778-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB CO. (US) | 2000-10-26 | — | — | WO | claimed |