Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 11/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604814 | 0.92 | LCK (0.60) | LCKCHRNA7 | |
| SCHEMBL6606810 | 0.88 | LCK (0.57) | LCKCHRNA7 | |
| SCHEMBL6608789 | 0.87 | LCK (0.66) | LCK | |
| SCHEMBL27562376 | 0.83 | RAB9A (0.64) | — | |
| SCHEMBL1540033 | 0.80 | LCK (0.74) | LCKCHRNA7L3MBTL1 | |
| SCHEMBL6605854 | 0.77 | LCK (0.53) | LCK | |
| SCHEMBL7631048 | 0.76 | LCK (0.61) | LCK | |
| SCHEMBL5607542 | 0.76 | LCK (0.71) | LCKCHRNA7 | |
| SCHEMBL6608382 | 0.76 | ALDH1A1 (0.46) | L3MBTL1 | |
| SCHEMBL27562374 | 0.76 | LCK (0.50) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169038-A4 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2004-10-13 | — | — | EP | claimed |
| EP-1169038-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-01-09 | — | — | EP | claimed |
| WO-2000062778-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB CO. (US) | 2000-10-26 | — | — | WO | claimed |