Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628458 | 0.86 | PKM (0.45) | LCKCISD2 | |
| SCHEMBL7626056 | 0.85 | LCK (0.45) | LCK | |
| SCHEMBL7631046 | 0.81 | LCK (0.70) | LCK | |
| SCHEMBL7635519 | 0.81 | LCK (0.57) | LCK | |
| SCHEMBL6058151 | 0.80 | LCK (0.55) | LCK | |
| SCHEMBL7623921 | 0.80 | LCK (0.63) | LCK | |
| SCHEMBL7631673 | 0.78 | LCK (0.46) | LCK | |
| SCHEMBL7632520 | 0.77 | LCK (0.43) | LCK | |
| SCHEMBL6608789 | 0.77 | LCK (0.66) | LCKCISD2 | |
| SCHEMBL7625987 | 0.77 | LCK (0.45) | LCKCISD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037632-A4 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-1037632-A1 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999024035-A1 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-05-20 | — | — | WO | disclosed |