Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.40 |
| ▸ | MC3R | P41968 | 5/20 | 0.38 |
| ▸ | MC5R | P33032 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679452 | 0.92 | MC4R (0.40) | MC4R | |
| SCHEMBL6606677 | 0.75 | MC4R (0.40) | MC4R | |
| SCHEMBL6604778 | 0.73 | MC4R (0.40) | MC4RMC3RMC5R | |
| SCHEMBL6607073 | 0.69 | MC4R (0.45) | MC4R | |
| SCHEMBL4682450 | 0.69 | MC4R (0.47) | MC4RMC3RMC5R | |
| SCHEMBL5337815 | 0.65 | L3MBTL1 (0.45) | MC4R | |
| SCHEMBL4678276 | 0.64 | MC4R (0.41) | MC4R | |
| SCHEMBL6156123 | 0.64 | KDM4E (0.48) | — | |
| SCHEMBL4681130 | 0.64 | MC4R (0.44) | MC4R | |
| SCHEMBL6604084 | 0.64 | MC4R (0.46) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417190-A1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgen Inc. (US) | 2004-05-12 | — | — | EP | claimed |
| WO-2003009850-A1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC. (US) | 2003-02-06 | — | — | WO | claimed |