SCHEMBL6604084

SCHEMBL6604084

CCCN(Cc1ccccc1N1CCN(C(=O)[CH]Cc2ccc(Cl)cc2)CC1)CC1CC1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MC4R P32245 14/20 0.46
TACR3 P29371 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4678276 0.89 MC4R (0.41) MC4R
SCHEMBL6604090 0.86 MC4R (0.52) MC4R
SCHEMBL4678279 0.84 MC4R (0.54) MC4R
SCHEMBL6602534 0.77 MC4R (0.64) MC4R
SCHEMBL4679456 0.76 MC4R (0.59) MC4R
SCHEMBL4677789 0.74 MC4R (0.53) MC4R
SCHEMBL6809533 0.74 MC4R (0.39) MC4R
SCHEMBL4677483 0.74 MC4R (0.47) MC4R
SCHEMBL4684736 0.72 MC4R (0.43) MC4R
SCHEMBL5337815 0.72 L3MBTL1 (0.45) MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1417190-A1 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR Amgen Inc. (US) 2004-05-12 EP claimed
WO-2003009850-A1 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEN INC. (US) 2003-02-06 WO claimed