Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749362 | 0.72 | — | — | |
| SCHEMBL13607839 | 0.70 | — | — | |
| Cyclohexane SCHEMBL10983411 | 0.69 | TP53 (0.73) | TP53 | |
| Diethylamine SCHEMBL27878566 | 0.69 | — | — | |
| SCHEMBL7738778 | 0.69 | NOS3 (0.34) | — | |
| SCHEMBL258115 | 0.69 | — | — | |
| SCHEMBL21114247 | 0.69 | NOS3 (0.34) | — | |
| SCHEMBL21114306 | 0.69 | NOS3 (0.34) | — | |
| SCHEMBL97287 | 0.69 | NOS3 (0.34) | — | |
| SCHEMBL7741554 | 0.69 | NOS3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1106614-B1 | 5-Membered heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER (US) | 2004-01-07 | — | — | EP | disclosed |
| US-6444677-B2 | TREATMENT OF INFLAMMATION, CARDIOVASCULAR DISEASE, PAIN, ETC. | PFIZER INC. | 2002-09-03 | — | — | US | disclosed |
| EP-1106614-A1 | 5-Membered heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. (US) | 2001-06-13 | — | — | EP | disclosed |