⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522136 | 0.97 | — | — | |
| SCHEMBL22572564 | 0.91 | — | — | |
| SCHEMBL20855149 | 0.84 | — | — | |
| SCHEMBL6604152 | 0.72 | TP53 (0.35) | — | |
| SCHEMBL247765 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL7658464 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL7625144 | 0.67 | KMT2A (0.42) | — | |
| SCHEMBL7671023 | 0.66 | TRIM24 (0.31) | — | |
| SCHEMBL6983120 | 0.65 | HRH3 (0.57) | — | |
| SCHEMBL258276 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124582-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |