Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5673114 | 0.93 | HTR3A (0.36) | HTR3AKCNH2 | |
| SCHEMBL5675103 | 0.84 | CHRNA7 (0.41) | HTR3ACHRNA7SMN1; SMN2 | |
| SCHEMBL6601516 | 0.83 | HRH3 (0.48) | HTR3ALMNASMN1; SMN2 | |
| Bromide SCHEMBL5675094 | 0.83 | CHRNA7 (0.40) | HTR3ACHRNA7SMN1; SMN2 | |
| Oxalic Acid SCHEMBL5675074 | 0.78 | HDAC3 (0.48) | HPGDSMN1; SMN2 | |
| SCHEMBL5358073 | 0.75 | CHRNA7 (0.36) | HTR3ACHRNA7SMN1; SMN2 | |
| SCHEMBL6542495 | 0.74 | HRH3 (0.42) | HTR3AKCNH2CHRNA7 | |
| SCHEMBL6600859 | 0.74 | HRH3 (0.46) | HTR3ACHRNA7SMN1; SMN2 | |
| Bromide SCHEMBL5673167 | 0.73 | HRH3 (0.41) | HTR3AKCNH2CHRNA7 | |
| SCHEMBL1689004 | 0.71 | CHRNA7 (0.64) | HTR3AKCNH2CHRNA7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289987-B1 | 4-(2-PHENYLTHIAZOL-5-YL)-1,4-DIAZABICYCLO- 3.2.2]NONANE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SYNTHELABO (FR) | 2004-05-19 | — | — | EP | disclosed |