Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522177 | 0.85 | PTPN1 (0.66) | PTPN1MEN1RAB9AKMT2ANR4A1 | |
| SCHEMBL19644240 | 0.85 | PTPN1 (0.66) | PTPN1MEN1RAB9AKMT2ANR4A1 | |
| SCHEMBL4961105 | 0.82 | PTPN1 (0.45) | PTPN1MEN1RAB9AKMT2ACYP2A6 | |
| SCHEMBL4607123 | 0.82 | ALDH1A1 (0.57) | PTPN1MEN1KMT2ANR4A1NR4A2 | |
| SCHEMBL29860832 | 0.82 | ALDH1A1 (0.57) | PTPN1MEN1KMT2ANR4A1NR4A2 | |
| SCHEMBL31625685 | 0.81 | PTPN1 (0.61) | PTPN1MEN1KMT2ANR4A1NR4A2 | |
| SCHEMBL2154228 | 0.81 | PTPN1 (0.61) | PTPN1MEN1KMT2ANR4A1NR4A2 | |
| SCHEMBL3917194 | 0.81 | PTPN1 (0.47) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL9062580 | 0.81 | MEN1 (0.43) | PTPN1MAOBMEN1RAB9AKMT2A | |
| SCHEMBL6847143 | 0.80 | ALDH1A1 (0.55) | PTPN1MEN1KMT2ANR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091956-B1 | MUSCARINIC ANTAGONISTS | SCHERING CORP (US) | 2004-08-04 | — | — | EP | disclosed |
| CN-1146559-C | Muscarinic antagonists | ���鹫˾ | 2004-04-21 | — | — | CN | disclosed |
| US-6451797-B1 | PIPERIDINE DERIVATIVES | SCHERING CORPORATION | 2002-09-17 | — | — | US | disclosed |
| CN-1314905-A | Muscarinic antagonists | SCHERING CORP (US) | 2001-09-26 | — | — | CN | disclosed |
| EP-1091956-A1 | MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 2001-04-18 | — | — | EP | disclosed |
| US-6066636-A | ALZHEIMER'S DISEASE | SCHERING CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| WO-2000000488-A1 | MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 2000-01-06 | — | — | WO | disclosed |