Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NCF1 | P14598 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.40 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6079350 | 0.99 | KDM4E (0.44) | KDM4EKMT2ANCF1L3MBTL1CSNK2A2 | |
| SCHEMBL6599066 | 0.87 | PIK3CA (0.52) | NCF1KDM4APIK3CAGAA | |
| SCHEMBL6605079 | 0.87 | KDM4E (0.47) | KDM4EKMT2ANCF1ALDH1A1HPGD | |
| SCHEMBL6591671 | 0.87 | KDM4A (0.48) | KDM4EKMT2ANCF1L3MBTL1KDM4A | |
| Hydrochloric Acid SCHEMBL6080507 | 0.86 | KDM4E (0.46) | KDM4EKMT2ANCF1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6079508 | 0.86 | KDM4A (0.47) | KDM4EKMT2ANCF1L3MBTL1KDM4A | |
| SCHEMBL6600666 | 0.86 | NCF1 (0.49) | KDM4EKMT2ANCF1L3MBTL1CSNK2A2 | |
| SCHEMBL6079496 | 0.85 | KDM4E (0.43) | KDM4EKMT2ANCF1L3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL6080392 | 0.85 | NCF1 (0.48) | KDM4EKMT2ANCF1L3MBTL1CSNK2A2 | |
| Hydrochloric Acid SCHEMBL6080061 | 0.83 | CSNK2A2 (0.44) | KDM4EKMT2ANCF1L3MBTL1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |