Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 3/20 | 0.48 |
| ▸ | NCF1 | P14598 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6079508 | 0.99 | KDM4A (0.47) | KDM4ANCF1KMT2AKDM4EPIK3CA | |
| SCHEMBL6604563 | 0.87 | KDM4E (0.46) | KDM4ANCF1KMT2AKDM4EPIK3CA | |
| SCHEMBL6079777 | 0.87 | KDM4E (0.47) | KDM4ANCF1KMT2AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6079350 | 0.86 | KDM4E (0.44) | KDM4ANCF1KMT2AKDM4EPIK3CA | |
| SCHEMBL6599066 | 0.85 | PIK3CA (0.52) | KDM4ANCF1PIK3CAPKM | |
| SCHEMBL6605079 | 0.85 | KDM4E (0.47) | NCF1KMT2AKDM4EHTR6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6080168 | 0.84 | HTR6 (0.45) | KDM4ANCF1KMT2AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6080507 | 0.84 | KDM4E (0.46) | NCF1KMT2AKDM4EMEN1HTR6 | |
| SCHEMBL27472343 | 0.82 | NCF1 (0.47) | NCF1KMT2AMEN1METAP1USP2 | |
| Hydrochloric Acid SCHEMBL6641278 | 0.81 | NCF1 (0.46) | NCF1KMT2AMEN1METAP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |