⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28950102 | 0.74 | — | — | |
| SCHEMBL8524496 | 0.66 | ALDH1A1 (0.32) | — | |
| SCHEMBL28950107 | 0.65 | ALDH1A1 (0.39) | — | |
| SCHEMBL13720346 | 0.62 | — | — | |
| SCHEMBL2043921 | 0.62 | — | — | |
| SCHEMBL23198636 | 0.59 | — | — | |
| SCHEMBL6850009 | 0.56 | — | — | |
| SCHEMBL13136762 | 0.56 | — | — | |
| SCHEMBL31439039 | 0.55 | — | — | |
| SCHEMBL2085606 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023291-B1 | DIPYRIDOIMIDAZOLDERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS | ORTHO MCNEIL PHARM INC (US) | 2004-05-26 | — | — | EP | disclosed |
| EP-1023291-A1 | DIPYRIDOIMIDAZOLDERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2000-08-02 | — | — | EP | disclosed |
| US-5968946-A | FUSED PYRROLO-IMIDAZOPYRIDINE DERIVATIVES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1999018105-A1 | DIPYRIDOIMIDAZOLDERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-04-15 | — | — | WO | disclosed |