Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608157 | 0.85 | SMN1; SMN2 (0.44) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL6983670 | 0.85 | SMN1; SMN2 (0.44) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL17803909 | 0.84 | AAK1 (0.50) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL6400709 | 0.84 | SYK (0.40) | AAK1CA1CA2CA7CTSS | |
| SCHEMBL6400733 | 0.82 | CTSK (0.44) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL30175074 | 0.82 | CA1 (0.39) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL19227630 | 0.82 | CA1 (0.58) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL6405983 | 0.81 | CA1 (0.46) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL14923598 | 0.81 | AAK1 (0.53) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL3375872 | 0.81 | AAK1 (0.53) | AAK1CA1CA2CA7CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |