Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 10/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608157 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2SYKCTSKCTSSCA1 | |
| SCHEMBL6400733 | 0.88 | CTSK (0.44) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL6400709 | 0.86 | SYK (0.40) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL30175074 | 0.85 | CA1 (0.39) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL6605636 | 0.85 | AAK1 (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2010010 | 0.82 | CYP1A2 (0.39) | SMN1; SMN2SYKCTSKCTSSCA1 | |
| SCHEMBL29890909 | 0.82 | CA1 (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9911449 | 0.81 | CA1 (0.52) | SYKCTSKCTSSCA1CA2 | |
| SCHEMBL6405983 | 0.81 | CA1 (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL16638817 | 0.80 | CTSK (0.45) | SMN1; SMN2SYKCTSKCTSSCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |