Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604479 | 0.92 | HRH1 (0.42) | HRH1KCNH2 | |
| SCHEMBL6603645 | 0.90 | HRH1 (0.41) | HRH1KCNH2 | |
| SCHEMBL6606267 | 0.74 | HRH1 (0.64) | HRH1KCNH2 | |
| SCHEMBL6607904 | 0.72 | HRH1 (0.44) | HRH1KCNH2 | |
| SCHEMBL6604991 | 0.71 | HRH1 (0.46) | HRH1 | |
| SCHEMBL17023772 | 0.70 | HRH1 (0.77) | HRH1KCNH2 | |
| SCHEMBL17023774 | 0.69 | HRH1 (0.79) | HRH1KCNH2 | |
| SCHEMBL6605503 | 0.69 | HRH1 (0.51) | HRH1 | |
| SCHEMBL14573192 | 0.69 | KDM4E (0.47) | HRH1KCNH2 | |
| SCHEMBL6606776 | 0.69 | HRH1 (0.56) | HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756370-B1 | POTENT 5-HT2A RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2004-06-29 | — | — | US | disclosed |
| EP-1202966-B1 | PIPERIDINE ALCOHOLS | MERCK PATENT GMBH (DE) | 2004-06-09 | — | — | EP | disclosed |
| EP-1202966-A1 | PIPERIDINE ALCOHOLS | MERCK PATENT GmbH (DE) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001014332-A1 | PIPERIDINE ALCOHOLS | MERCK PATENT GMBH (DE) | 2001-03-01 | — | — | WO | disclosed |