Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983462 | 0.77 | PTPN2 (0.56) | PTPN2PTPN1PTPN5SMN1; SMN2ALDH1A1 | |
| SCHEMBL11050599 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA9GAASMN1; SMN2 | |
| SCHEMBL4815560 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA9GAASMN1; SMN2 | |
| SCHEMBL3545668 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA9GAASMN1; SMN2 | |
| SCHEMBL8484861 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA9GAASMN1; SMN2 | |
| SCHEMBL8483813 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA9GAASMN1; SMN2 | |
| SCHEMBL4951882 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA9GAASMN1; SMN2 | |
| SCHEMBL4812770 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA9GAASMN1; SMN2 | |
| SCHEMBL4954181 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA9GAASMN1; SMN2 | |
| SCHEMBL6607741 | 0.76 | MEN1 (0.47) | CA12CA1CA9KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-B1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |