SCHEMBL660629

SCHEMBL660629

Clc1cc2ccsc2cn1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.38
CYP2A6 P11509 2/20 0.37
KDM1A O60341 1/20 0.37
KDM4E B2RXH2 3/20 0.37
GRM4 Q14833 1/20 0.37
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
PPARG P37231 1/20 0.35
HTT P42858 1/20 0.35
NCOA2 Q15596 1/20 0.35
NCOA1 Q15788 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
PIK3CD O00329 1/20 0.35
AXL P30530 1/20 0.34
MKNK1 Q9BUB5 1/20 0.34
MKNK2 Q9HBH9 1/20 0.34
LMNA P02545 1/20 0.34
CHRNA7 P36544 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17464091 0.83 KDM1A (0.37) DYRK1ACYP2A6KDM1AKDM4EGRM4
SCHEMBL157982 0.75 CYP2A6 (0.47) DYRK1ACYP2A6KDM1AKDM4EGRM4
SCHEMBL657606 0.75 DYRK1A (0.50) DYRK1ACYP2A6KDM1AKDM4EGRM4
SCHEMBL8114596 0.75 DYRK1A (0.38) DYRK1ACYP2A6KDM1AKDM4EGRM4
SCHEMBL659606 0.75 DYRK1A (0.38) DYRK1ACYP2A6KDM1AKDM4EGRM4
SCHEMBL659466 0.75 GRM4 (0.40) DYRK1ACYP2A6KDM1AKDM4EGRM4
SCHEMBL21666073 0.71 KDM4E (0.38) DYRK1ACYP2A6KDM1AKDM4EGRM4
SCHEMBL22430462 0.71 KDM4E (0.41) DYRK1ACYP2A6KDM1AKDM4EGRM4
SCHEMBL20631749 0.71 KDM4E (0.41) DYRK1ACYP2A6KDM4EGRM4MAPT
SCHEMBL18237423 0.71 KDM1A (0.39) DYRK1ACYP2A6KDM1AKDM4EGRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11713291-B2 Compound for organic electronic device, organic electronic device using same, and electronic apparatus thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-08-01 US disclosed
US-11713291-B2 Compound for organic electronic device, organic electronic device using same, and electronic apparatus thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-08-01 US disclosed
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 US disclosed
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 US disclosed
US-11552253-B2 Compound for organic electric device, organic electric device using same, and electronic device DUK SAN NEOLUX CO., LTD. (KR) 2023-01-10 US disclosed
US-20210242410-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2021-08-05 US disclosed
US-11024810-B2 Compound for organic electronic element, organic electronic element using same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2021-06-01 US disclosed
US-11024805-B2 Compound for organic electric element, organic electric element using same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2021-06-01 US disclosed
US-11008280-B2 Compound for organic electric element, organic electric element using same, and electronic device comprising same organic electronic element DUK SAN NEOLUX CO., LTD. (KR) 2021-05-18 US disclosed
US-10995069-B2 Compound for organic electric element, organic electric element using same, and electronic device comprising same DUK SAN NEOLUX CO., LTD. (KR) 2021-05-04 US disclosed
WO-2017171397-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2017-10-05 WO disclosed
WO-2017160089-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFROM 덕산네오룩스 주식회사 2017-09-21 WO disclosed
WO-2017153601-A1 BICYCLIC COMPOUNDS FOR DIAGNOSIS AND THERAPY AC IMMUNE SA (CH) 2017-09-14 WO disclosed
WO-2017095075-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE 덕산네오룩스 주식회사 2017-06-08 WO disclosed
US-20160028020-A1 ORGANIC ELECTRONIC ELEMENT AND AN ELECTRONIC DEVICE COMPRISING IT DUK SAN NEOLUX CO., LTD. (KR) 2016-01-28 US disclosed
US-20160028020-A1 ORGANIC ELECTRONIC ELEMENT AND AN ELECTRONIC DEVICE COMPRISING IT DUK SAN NEOLUX CO., LTD. (KR) 2016-01-28 US disclosed
US-8378104-B2 7-aminofuropyridine derivatives OSI Pharmaceuticals, LLC (US) 2013-02-19 US disclosed
EP-2534156-A1 7-AMINOFUROPYRIDINE DERIVATIVES OSI Pharmaceuticals, LLC (US) 2012-12-19 EP disclosed
US-20120046267-A1 7-AMINOFUROPYRIDINE DERIVATIVES OSI PHARMACEUTICALS, INC. 2012-02-23 US disclosed
WO-2011100502-A1 7-AMINOFUROPYRIDINE DERIVATIVES OSI Pharmaceuticals, LLC (US) 2011-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11713291-B2 Compound for organic electronic device, organic electronic device using same, and electronic apparatus thereof PIEZO1, ORAI2, EXOC1 DYRK1A 3962/4885CYP2A6 3062/4885KDM1A 2871/4885
US-11024805-B2 Compound for organic electric element, organic electric element using same, and electronic device thereof PIEZO1, ORAI2, PER2 DYRK1A 3896/4885CYP2A6 3615/4885KDM1A 2716/4885
US-20120046267-A1 7-AMINOFUROPYRIDINE DERIVATIVES MAP3K5, STK17A, MAPKAPK5 DYRK1A 2154/4885CYP2A6 1912/4885KDM1A 169/4885
US-20210242410-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF PIEZO1, ORAI2, OR10J3 DYRK1A 3654/4885CYP2A6 3746/4885KDM1A 3606/4885
US-10995069-B2 Compound for organic electric element, organic electric element using same, and electronic device comprising same ORAI2, PIEZO1, CACNA2D2 DYRK1A 3520/4885CYP2A6 2303/4885KDM1A 2038/4885
US-11552253-B2 Compound for organic electric device, organic electric device using same, and electronic device OR10J3, OR51E2, ORAI2 DYRK1A 3084/4885CYP2A6 2405/4885KDM1A 536/4885
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE OR10J3, OR51E2, ORAI2 DYRK1A 3133/4885CYP2A6 2554/4885KDM1A 497/4885
US-11008280-B2 Compound for organic electric element, organic electric element using same, and electronic device comprising same organic electronic element ORAI2, PIEZO1, ORC3 DYRK1A 2549/4885CYP2A6 3330/4885KDM1A 2518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.